美国路易斯安那州立大学（Louisiana State University）Donghui Zhang教授学术报告
发布时间：2016-06-20 字体大小T|T
应甘肃省有色金属化学与资源利用重点实验室、化学化工学院邀请，美国路易斯安那州立大学（Louisiana State University）Donghui Zhang教授来我校进行学术交流并作学术报告，欢迎广大师生参加。
报 告 人：Prof. Donghui Zhang
报告题目：A Journey into the World of Peptidomimetic Polymers: Twist and Turns and Discovery
报告时间：2016年6月22日（星期三）15: 00
报告地点：第一化学楼1001报告厅
简介：
Dr. Donghui Zhang is an Associate Professor of Chemistry at the Louisiana State University. She obtained B.S. in Chemistry from Peking University in 1998 and Ph.D. in Organometallic Chemistry from Dartmouth College in 2003 and did one and half year postdoctoral research at University of Minnesota on the synthesis and characterization of polymers from biorenewable source materials. She joined LSU in 2007 after a two-year stint as a research faculty in New Mexico State University. Her research interests include polymer catalysis, synthesis and characterization of biomimetic, bioinspired and bio-relevant functional polymers, high precision macromolecules.In her spare time, Donghui enjoys outdoor activities and sports (badminton, basketball, swimming, running and yoga), reading and spending time with family and friends.
摘要：
Peptidomimetic polymers refer to a broad class of polymers whose molecular structures are similar to those of polypeptides. They emulate polypeptides in their ability to fold into higher order structures. Previous studies have shown that these polymers are backbone degradable, often biocompatible and in some cases thermally processable. This presentation will be focused on our recent findings in the design, synthesis and characterization of polypeptoids, a class of emerging peptidomimetic polymers featuring N-substituted polyglycine backbones with either proteinogenic or synthetic sidechains. The physicochemical properties of the polypeptoids are strongly dependent on the side chain structures, enabling systematic tuning of the polymer solubility, crystallinity and backbone conformations. Examples will be given on the development oforgano-mediated controlled polymerization methods towards structurally well-defined polypeptoids and the design and development of functional polypeptoid materials for targeted biomedical applications (e.g., injectable polypeptoid thermo-gels based on a binodal micellar network structure).
